937 research outputs found
Influence of corrosion and creep on intergranular fatigue crack path in 2XXX aluminium alloys
In this paper, two examples of the influence of time-dependent processes on crack path in two 2XXX aluminium alloys are presented. The first example is concerned with corrosionâfatigue crack growth resistance of a 2024 T351 alloy cracked in the SâL direction in 3.5% NaCl solution at free corrosion potential. The second example deals with the elevated temperature crack growth resistance of a 2650 T6 alloy that might be used in future supersonic aircraft fuselage panels. The common idea is to correlate quantitative measurements of relevant fractographic features of crack path to the effects of time-dependent processes on crack growth rates
Amoebal pathogens as emerging causal agents of pneumonia
Despite using modern microbiological diagnostic approaches, the aetiological agents of pneumonia remain unidentified in about 50% of cases. Some bacteria that grow poorly or not at all in axenic media used in routine clinical bacteriology laboratory but which can develop inside amoebae may be the agents of these lower respiratory tract infections (RTIs) of unexplained aetiology. Such amoebae-resisting bacteria, which coevolved with amoebae to resist their microbicidal machinery, may have developed virulence traits that help them survive within human macrophages, i.e. the first line of innate immune defence in the lung. We review here the current evidence for the emerging pathogenic role of various amoebae-resisting microorganisms as agents of RTIs in humans. Specifically, we discuss the emerging pathogenic roles of Legionella-like amoebal pathogens, novel Chlamydiae (Parachlamydia acanthamoebae, Simkania negevensis), waterborne mycobacteria and Bradyrhizobiaceae (Bosea and Afipia spp.
What can best explain the prevalence of bilateralism in the investment regime?
Most efforts to negotiate a multilateral agreement on the liberalization and protection of
investment have failed despite the fact that there are more than 2,400 bilateral investment treaties
in existence. We have coined this phenomenon the âlateralism paradox.â Within this article, we
consider five hypotheses that focus respectively on power asymmetries, incentives for defection,
strategic linkages, domestic constraints, and ongoing adaptation. We found that the first four
explanations are not supported by empirical evidence from the post-NAFTA period. We conclude
that bilateralism appears to be the only feasible approach for negotiating investment rules, as well
as the most sensible process to ensure continuous and dynamic adaptation
A dedicated constrained optimization method for 3D reflexion tomography
International audienceSeismic reflection tomography is a method for the determination of a subsurface velocity model from the traveltimes of seismic waves reflecting on geological interfaces. From an optimization viewpoint, the problem consists in minimizing a nonlinear least-squares function measuring the mismatch between observed traveltimes and those calculated by raytracing in this model. The introduction of a priori information on the model is crucial to reduce the under-determination. The contribution of this paper is to introduce a technique able to take into account geological a priori information in the reflection tomography problem expressed as constraints in the optimization problem. This constrained optimization is based on a Gauss-Newton Sequential Quadratic Programming approach. At each Gauss-Newton step, a solution to a strictly convex quadratic optimization problem subject to linear constraints is computed thanks to an augmented Lagrangian relaxation method. Our choice for this optimization method is motivated and its original aspects are described. The efficiency of the method is shown on applications on a 2D OBC real data set and on a 3D real data set: the introduction of constraints coming both from well logs and from geological knowledge allows to reduce the under-determination of the 2 inverse problems. Introduction Reflection tomography allows to determine a velocity model from the traveltimes of seismic waves reflecting on geological interfaces. This inverse problem is formulated as a nonlinear least-squares function which measures the mismatch between observed traveltimes and traveltimes computed by ray tracing method. This method has been successfully applied to real data sets (Ehinger et al, 2001, Broto et al, 2003). Nevertheless, the under-determination of the inverse problem generally requires the introduction of additional information on the model to reduce the number of admissible models. Penalization terms modelling this information can be added to the seismic terms in the objective functions but the tuning of the penalization weights may be tricky. In this paper, we propose to handle the a priori information by the introduction of equality and inequality constraints in the optimization process. This approach allows to introduce lot of constraints of different types, provided we have at our disposal an adequate constrained optimization method. We developed an original method designed for the tomographic inverse problem which presents the following characteristics: it is a large scale problem (10000-50000 unknowns), the forward operator is nonlinear and its computation may be expensive (large number of source-receiver couples, up to 500000), the problem is ill-conditioned. In the first part of this paper, the chosen method is motivated and its original aspects are shortly described (for further details, refer to Delbos et al, 2004). Applications on a 2D PP/PS real data set and on a 3D PP real data set are presented in a second part
Integration of control loops in coupled field circuit model to study magnetic devices supplied by power electronic converter and their control
In this paper, we present a method to take into account the feedback control in software developed from coupled field circuit models. The implementation of control loops is done in a software which is able to simulate electromagnetic devices associated with power electronic circuits having a time dependent topology. The control strategy is implemented in a discreteâtime version and can manage all controllable electronic switches by means of different electric or magnetic quantities calculated during the simulation (flux, currents, voltages,ââŠ). Electrical systems involving magnetic devices, power electronic converters and their control devices can be simulated in presence of phenomena such as eddy currents or saturation of the magnetic materials
Lâinfluence de la gouvernance sur la capacitĂ© de changement du systĂšme de soins : lâexemple de lâimplantation des groupes de mĂ©decine de famille
Cette thĂšse sâintĂ©resse Ă la gouvernance de changements en contextes pluralistes. Nous souhaitons mieux comprendre lâexercice de gouvernance dĂ©ployĂ© pour dĂ©velopper et implanter un changement par le biais dâune politique publique visant la transformation dâorganisations pluralistes. Pour ce faire, nous Ă©tudions lâĂ©mergence et lâimplantation de la politique encadrant la crĂ©ation de groupes de mĂ©decine de famille (GMF) Ă lâaide dâĂ©tudes de cas correspondant Ă cinq GMF. Les cas sont informĂ©s par plus de cents entrevues rĂ©alisĂ©es en deux vagues ainsi que par une analyse documentaire et des questionnaires portant sur lâorganisation du GMF. Trois articles constituent le cĆur de la thĂšse.
Dans le premier article, nous proposons une analyse de lâĂ©mergence et de lâimplantation de la politique GMF Ă lâaide dâune perspective processuelle et contextuelle dĂ©veloppĂ©e Ă partir du champ du changement organisationnel, tel quâĂ©tudiĂ© en thĂ©orie des organisations. Les rĂ©sultats dĂ©montrent que la gestion du changement en contexte pluraliste est liĂ©e Ă de multiples processus prescrits et construits. Nous avons qualifiĂ© ce phĂ©nomĂšne de rĂ©gulation de lâaction social (regulation of collective action). La conceptualisation dĂ©veloppĂ©e et les rĂ©sultats de lâanalyse permettent de mieux comprendre les interactions entre les processus, le contexte et la nature du changement.
Le deuxiĂšme article propose une conceptualisation de la gouvernance permettant lâĂ©tude de la gouvernance en contextes pluralistes. La conceptualisation de la gouvernance proposĂ©e tire profit de plusieurs courants des sciences politiques et de lâadministration publique. Elle considĂšre la gouvernance comme un ensemble de processus auxquels participent plusieurs acteurs dĂ©tenant des capacitĂ©s variables de gouvernance. Ces processus Ă©mergent des actions des acteurs et des instruments quâils mobilisent. Ils permettent la rĂ©alisation des fonctions de la gouvernance (la prospective, la prise de dĂ©cisions ainsi que la rĂ©gulation) assurant la coordination de lâaction collective.
Le troisiĂšme article propose, comme le premier, une analyse de lâĂ©mergence et de lâimplantation de la politique mais cette fois Ă lâaide de la conceptualisation de la gouvernance dĂ©veloppĂ©e dans lâarticle prĂ©cĂ©dent. Nos rĂ©sultats permettent des apprentissages particuliers concernant les diffĂ©rentes fonctions de la gouvernance et les processus permettant leur rĂ©alisation. Ils rĂ©vĂšlent lâinfluence du pluralisme sur les diffĂ©rentes fonctions de gouvernance. Dans un tel contexte, la fonction de rĂ©gulation sâexerce de façon indirecte et est Ă©troitement liĂ©e aux fonctions de prospective et de prise de dĂ©cisions. Ces fonctions rendent possibles les apprentissages et le dĂ©veloppement de consensus nĂ©cessaires Ă lâaction collective. Lâanalyse des actions et des instruments a permis de mieux comprendre les multiples formes quâils prennent, en lien avec les contextes dans lesquels ils sont mobilisĂ©s. Les instruments indirects permettent les interactions (p. ex. commission dâĂ©tude, comitĂ© ou rĂ©union) et la formalisation dâententes entre acteurs (p. ex. des contrats ou des protocoles de soins). Ils se sont rĂ©vĂ©lĂ©s fondamentaux pour coordonner les diffĂ©rents acteurs participant Ă la gouvernance, et ce tant aux niveaux organisationnel quâinter organisationnel.
Les rĂ©sultats dĂ©montrent que les deux conceptualisations contribuent Ă lâĂ©tude de la gouvernance du changement. Nous avons dĂ©veloppĂ© deux perspectives inspirĂ©es par les sciences politiques, lâadministration publique et la thĂ©orie des organisations et les analyses quâelles ont permises ont rĂ©vĂ©lĂ© leur complĂ©mentaritĂ©. Les rĂ©sultats permettent de mieux comprendre les processus impliquĂ©s dans un tel changement ainsi que leur lien avec les efforts dĂ©ployĂ©s aux diffĂ©rents niveaux par les acteurs mobilisant leurs capacitĂ©s de gouvernance pour influencer et construire la politique GMF.This thesis is concerned with the governance of change in pluralistic contexts. We wanted to gain a better understanding of the governance processes utilised to develop and implement a public policy aimed at transforming pluralistic organisations. To this end, we conducted a multiple-case study of the emergence and implementation of a policy supporting the creation of family medicine groups (FMG) as it unfolded in five FMGs. The case studies were informed by over 100 interviews conducted in two periods in time as well as from an analysis of documents and questionnaires relating to the organisation of the FMGs. This thesis is essentially composed of three articles.
In the first article, we propose an analysis of the emergence and implementation of the FMG policy based on a combined processual-contextual perspective, which has its roots in the field of organisational change, as studied in organisational theory. The results demonstrated that the management of change in a pluralistic context is associated with multiple prescribed and constructed processes. We termed this phenomenon a regulation of collective action. The conceptual framework we developed enabled an analysis which in turn fostered a more enlightened understanding of the interactions that take place between processes, the context and the nature of change.
The second article proposes a conceptualisation of governance that enables it to be studied in pluralistic contexts. This framework draws from several branches of political science and public administration. It considers governance as the set of processes involving the participation of many actors, who possess varying degrees of governance capacities. These governance processes are manifested in actorsâ actions and the instruments they mobilise. Furthermore, the governance processes consist of three types of functionsâavenue-prospecting, decision-making and regulationâwhich together serve to coordinate collective action.
Like the first article, the third proposes an analysis of the emergence and implementation of a policy; however this article incorporates the framework of governance developed in the preceding article. Our analyses yielded some novel findings about the various functions of governance and the processes that lead to their realisation. Specifically, they revealed how the pluralistic context influences and shapes governance functions. In such contexts, the regulation function was found to be carried out in an indirect manner and to be closely tied to the functions of avenue-prospectings and decision making. These functions fostered the knowledge gathering and the consensus building needed to mobilise collective action and were manifested in the use of governance instruments. An analysis of actorsâ actions and the instruments they used gave us insight into the many forms that such actions and instruments can take as well as the contexts in which they may be mobilised. Indirect instruments allowed for interactions (e.g. task force, committee or meeting) and the formalisation of agreements between actors (e.g. contracts, care protocols). These instruments proved to be fundamental to the coordination of the various actors participating in governance, both within organisations and between them.
Our results demonstrate that the two frameworks contribute significantly to the study of change governance. We developed two conceptualisations inspired from political science, public administration and organisational theory, and the analyses they enabled revealed how the two frameworks complement each other. These results have given us a more clarified understanding of the processes involved in such a systemic change as well as the relationship between these processes and the efforts deployed at various levels of governance by actors exercising their capacity to influence or shape a far-reaching public policy
Proof CertiïŹcation in Zenon Modulo: When Achilles Uses Deduction Modulo to Outrun the Tortoise with Shorter Steps
International audienceWe present the certifying part of the Zenon Modulo automated theorem prover, which is an extension of the Zenon tableau-based first order automated theorem prover to deduction modulo. The theory of deduction modulo is an extension of predicate calculus, which allows us to rewrite terms as well as propositions, and which is well suited for proof search in axiomatic theories, as it turns axioms into rewrite rules. In addition, deduction modulo allows Zenon Modulo to compress proofs by making computations implicit in proofs. To certify these proofs, we use Dedukti, an external proof checker for the λΠ-calculus modulo, which can deal natively with proofs in deduction modulo. To assess our approach, we rely on some experimental results obtained on the benchmarks provided by the TPTP library
A possible alternative method for collecting mosquito larvae in rice fields
BACKGROUND: Rice fields are efficient breeding places for malaria vectors in Madagascar. In order to establish as easily as possible if a rice field is an effective larval site for anophelines, we compared classical dipping versus a net as methods of collecting larvae. RESULTS: Using similar collecting procedures, we found that the total number of anopheline larvae collected with the net was exactly double (174/87) that collected by dipping. The number of anopheline species collected was also greater with a net. CONCLUSIONS: The net is an effective means of collecting anopheline larvae and can be used for qualitative ecological studies and to rapidly determine which rice fields are containing malaria vectors
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